Kristi L Manjarrez Selected Research

ALPN-101

1/2021

First-in-human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN-101, a dual CD28/ICOS antagonist, in healthy adult subjects.

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Kristi L Manjarrez Research Topics

Disease

3	Neoplasms (Cancer) 01/2017 - 07/2014
2	Squamous Cell Carcinoma of Head and Neck 11/2018 - 05/2017
2	Chills 11/2018 - 07/2014
2	Injection Site Reaction 11/2018 - 07/2014
2	Fever (Fevers) 11/2018 - 07/2014
2	Ovarian Neoplasms (Ovarian Cancer) 01/2017 - 07/2014
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Anemia 11/2018
1	Exanthema (Rash) 11/2018
1	Drug-Related Side Effects and Adverse Reactions 05/2017
1	Lymphoma (Lymphomas) 07/2014
1	Human Influenza (Influenza) 07/2014
1	Head and Neck Neoplasms (Head and Neck Cancer) 07/2014

Drug/Important Bio-Agent (IBA)

5	VTX-2337IBA 11/2018 - 07/2014
3	Cetuximab (Erbitux)FDA Link 11/2018 - 07/2014
2	Biomarkers (Surrogate Marker)IBA 11/2018 - 12/2015
2	Toll-Like Receptor 8IBA 12/2015 - 07/2014
1	ALPN-101IBA 01/2021
1	Toll-Like Receptor AgonistsIBA 05/2017
1	Toll-Like Receptors (Toll-Like Receptor)IBA 05/2017
1	1-dodecylpyridoxal (PLD)IBA 01/2017
1	Antineoplastic Agents (Antineoplastics)IBA 01/2017
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2015
1	Cytotoxins (Cytolysins)IBA 12/2015
1	Interleukin-6 (Interleukin 6)IBA 12/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2014
1	PlatinumIBA 07/2014
1	Pharmaceutical PreparationsIBA 07/2014

Therapy/Procedure

3	Immunotherapy 11/2018 - 12/2015
1	Combination Drug Therapy (Combination Chemotherapy) 11/2018
1	Therapeutics 05/2017
1	Drug Therapy (Chemotherapy) 07/2014